With the recent advances in virtual reality technology such as the Oculus Rift, many video games are starting to design their user experience around an in-the-moment feel. Many of these games have been horror games, one of the first being "Amnesia: The Dark Descent". The game takes a lot of common aesthetic elements as well as themes from classic horror literature and films to create the same atmosphere.
The first and most obvious thing Amnesia uses from the horror genre is the creepy castle motif, as well as the feeling of isolation we talked about in class. There is even a larger parallel to young frankenstein: the castle is in Europe, the main character is a man coming to terms with his heritage / past, the castle is explored from room to room to uncover clues and delve deeper into the castle.
The castle itself is modeled after 18th century gothic architecture and much of the game is spent in the dark waiting for a creepy monster to pop out. The passages of the castle are narrow, filled with candles and suits of armor, and give the uneasy feeling that something might be following you at all times (think Alien).
A lot of the game's storyline is based around the gothic theme of life and death. The main antagonist is a sort of otherworldly spirit, and much of the scariness stems from human mortality and the opening of a monster portal. The gate cannot be opened without the blood of humans however which sort of brings the "science" of horror, much like the making of frankenstein, back into the game.
This is only the tip of the iceberg as many other games are taking a more gothic / horror approach to games (such as Dark Souls II or Diablo 3).